Background: The factors influencing parents’ willingness to enroll their children in biobanks are poorly understood. This study sought to assess parents’ willingness to enroll their children, and their perceived benefits, concerns, and information needs under different consent and data-sharing scenarios, and to identify factors associated with willingness. Methods: This large, experimental survey of patients at the 11 eMERGE Network sites used a disproportionate stratified sampling scheme to enrich the sample with historically underrepresented groups. Participants were randomized to receive one of (...) three consent and data-sharing scenarios. Results: In total, 90,000 surveys were mailed and 13,000 individuals responded (15.8% response rate). 5737 respondents were parents of minor children. Overall, 55% (95% confidence interval 50–59%) of parents were willing to enroll their youngest minor child in a hypothetical biobank; willingness did not differ between consent and data-sharing scenarios. Lower educational attainment, higher religiosity, lower trust, worries about privacy, and attitudes about benefits, concerns, and information needs were independently associated with less willingness to allow their child to participate. Of parents who were willing to participate themselves, 25% were not willing to allow their child to participate. Being willing to participate but not willing to allow one’s child to participate was independently associated with multiple factors, including race, lower educational attainment, lower annual household income, public health care insurance, and higher religiosity. Conclusions: Fifty-five percent of parents were willing to allow their youngest minor child to participate in a hypothetical biobank. Building trust, protecting privacy, and addressing attitudes may increase enrollment and diversity in pediatric biobanks. (shrink)

This is a forthright and refreshing book. It aims to bring the clarifying power of analytic philosophy to the luxuriant variety in one part of Meinong's ontology. Parson's title is meant to be read literally: it is not propositions, numbers, universals or sets, but only particular objects whose nonexistence concerns him. Parsons gives two reasons for believing that there are nonexistent objects. First, we match objects against the sets of their properties. When every existing object has been listed, we carry (...) on making sets of properties. These additional sets correlate with nonexistent objects, e.g., the golden mountain. Second, there are the many occasions when we use names or definite descriptions to characterize truly such nonexistent objects as Pegasus and Sherlock Holmes. There is, says Parsons, no satisfactory reason for rephrasing these sentences when we refuse to paraphrase sentences of the same form having existing objects as their referents. (shrink)

These books entertain as well as teach philosophical wisdom by looking closely at entertainment icons.

Michael Dummett has claimed that analytic philosophy is distinguished from other schools in its belief that a comprehensive philosophical account of thought can only be attained by developing a philosophical account of language. Dummett himself argues persuasively for the priority-of-Ianguage thesis. This, in effect, metaphilosophical position is of special importance for his more straightforwardly philosophical views, for he holds that philosophical investigations of the concepts of objectivity and reality grow directly out of the philosophy of thought. But I argue that (...) some of what Dummett says about the priority of language over thought is problematic, that there may yet be a serious role for concepts within the theory of meaning, and that Dummett’s failure to acknowledge this role both hobbles his account of linguistic understanding and has deleterious consequences for his discussions of metaphysical realism-robbing him of the resources with which he might have avoided some of his anti-realist conclusions. (shrink)

Editors and commentators ancient and modern have not responded very well to the challenge of the two riddles which round off the contest between Damoetas and Menalcas at the end of Eclogue 3 . The first is generally regarded as impossibly difficult; the second as impossibly easy. Critics take refuge in quoting Servius' despairing statement: sciendum aenigmata haec sicuti pleraque carere aperta solutione. Yet it is most unlikely that Virgil would introduce insoluble or meaningless riddles into the Bucolica. If there (...) is no solution the lines become pointless, even tasteless; and these are not epithets to be applied lightly to Virgil's poetry. (shrink)

Although neglected in the annals of political theory, the struggle between decentralized government and monarchy in the Hebrew scriptures parallels the tensions inherent in classic works of Western political theory from Plato to the American founders. The biblical authors provided lessons beyond the religious sphere, addressing the shared duties of religion and state in developing human virtue, the proper relationships between God, government and the people, and the best forms of government to achieve these objectives. This essay analyses the debate (...) over kingship in ancient Israel as presented in the biblical narratives, demonstrating that the Israelites’ story is important not only as a religious text, but as political theory, and that the questions asked in these texts have retained their relevance. (shrink)